Thanks to the guidance found on these forums and everyone's experiences, I was able to get a GTX 980 setup running perfectly with the AKiTiO case opened up and PSU barrel plug modification. I'm powering external monitors with it on both Windows 10 and OS X. Thanks everyone for posting their experiences so we can all learn! I do have one issue I wanted to see if anyone has a solution for. Whenever I shutdown / reboot the computer I always end up having to shut the Macbook Pro off / on multiple times before I can get the system to post and start loading the OS if the eGPU is hooked into a Thunderbolt 2 port. I'm using a late 2013 MBPr 15" with a built in 750m. This happens if I'm trying to boot into either OSX or Windows. Everything starts normally on the first try if the eGPU is disconnected (though Windows makes me reinstall drivers if I start it up without the eGPU and then start it again later with it... so I try to avoid that). Edit: The GPU is a eVGA Geforce GTX 980 FTW Has anyone come across this problem before or have any ideas? Thanks~