So I went out and bought a ThinkPad E560 motherboard and all other necessary parts (ram, ssd, fan, cables, etc). The parts alone works great! It's an i7 (skylake) model with amd r7 m370.
Now I already had an r9 290 and a GDC beast v.8 with a m.2 adapter and monitor. It was more or less plug n' play on my previous laptop. But now I'm having a really hard time making it work.
I could really use some expert help here!