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Hi. I have successfully setup an external graphics card with my macbook pro (late 2013), Akitio Thunderbold PCI enclosure and a asus 750 ti. On the 750 ti Fist let me explain that this card requires the 6 pin power inputs as well as pci power. Power I'm not using a riser (riser was casing crashes and instability, even a capacitated one). I'm using a 600w aTX psu (paperclipped) to barrel plug and 6-pin. I was exteremly nervous about doing this, just twisting the electrical wire together like speaker wire. Not sure if it's a good idea (insulated with electrical tape of course). It's good to have another piece of electrical equipment to test on before plugging into your expensive pci enclosure. If it blows up, you did it wrong. I had an old wireless repeater with the same barrel plug input and was please to see it turn on. Using a powered PCI riser bought from ebay introduced crashes / freezes. My internet and graphics and other assorted parts of teh system would lag strangely, perform badly, and then a system crash would inevitably follow at some stage. Removing the riser removed the issue. Startup As long as the card has had a few seconds to warm up, there are no issues. Optimus The optimus hack was straightforward. I'm using goalque's automatic script. I'm using an external display, and I think the computer uses the egpu for the internal display although not certain. Issues Occasional graphics crashes / freezes and system freezes. Fairly stable. Overclocking I can add about 200mhz onto the clock and 150 onto the memory without issue. The card rarely seems to run over 50% except in benchmarks.