So I'm running a Zotac GTX 960 via Akitio box on a 13" rMBP late 2013 model + latest version El Capitan for a few months now. The Zotac drives 2x 28" 4k monitors @ 60Hz, I use this setup for work to get more real estate, not to play games. The performance was decent, switching spaces and using mission control is laggy. I never use the internal display, just close the laptop which would leave the screen on. In a frustrating search to improve spaces / mission control performance, I looked for options to disable the internal monitor as it is not used, but might take up CPU/ GPU (?) resources. I found this program https://github.com/Eun/DisableMonitor to disable the internal monitor and all the spaces / mission control issues are gone :-). The OS responds very snappy now. One glitch: there is a desktop background picture-in-picture on the primary screen with the size of about 1/4th of the screen, but in doesn't influence app behaviour. I was wondering what causes this performance boost. The internal display was still powered by the internal GPU. I could not see significant changes in CPU loads causes by WindowServer or other processes, around 32-36% during repeated mission control usage. Also, 'About This Mac' still report the internal display as active / online. Off-topic question: unplugging the Akitio Thunderbolt cable instantly causes a system crash, I have to shut down the laptop first. Same with plugging it in while on, sometimes is crashes the system, most of the times nothing happens until a reboot. Is there already a fix for this? I used goalque's automate-eGPU.sh script for installation.