Not sure if you guys know of this app that ejohnson from the NBR forums found on some russian site. It changes the AlienFX lights colour to match whatever is on your screen. It calculates the average colour that is shown on your screen and sends that colour to the alienFX controller to display.
I've tried it and it works on my M17x R2 except for the power button and alienhead on the lid. Very interesting especially if you have alternating wallpapers with different colours Its a bit too distracting if you're watching a movie or playing a game though. Although it will should work well with say a fullscreen visualisation on your fave music player
theHelios also from NBR set it up for us Alienware users and can be downloaded from his private dropbox below.
http://dl.dropbox.com/u/1089880/Lightpack AlienFX.zip
To see it in action check it on youtube
The original thread can be found here.